[Neuroprotective effects of peptides bioregulators in people of various age]

Adv Gerontol. 2013;26(4):671-8.
[Article in Russian]

Abstract

The review presents comparative characteristics of 2 peptide neuroprotective groups: polypeptide complexes (cortexin, cerebrolizin) and short peptides (semax, kortagen, pinealon). The data of clinical applying of peptides in elderly and old age people and cellular and molecular mechanisms of their neuroprotective activity is described.

Publication types

  • Review

MeSH terms

  • Adrenocorticotropic Hormone / analogs & derivatives
  • Adrenocorticotropic Hormone / pharmacology
  • Aged
  • Amino Acids / pharmacology
  • Brain* / drug effects
  • Brain* / pathology
  • Cellular Senescence / drug effects*
  • Central Nervous System Diseases / drug therapy*
  • Central Nervous System Diseases / pathology
  • Humans
  • Intercellular Signaling Peptides and Proteins
  • Neuroprotective Agents / pharmacology*
  • Oligopeptides / pharmacology
  • Outcome Assessment, Health Care
  • Peptide Fragments / pharmacology
  • Peptides / pharmacology
  • Randomized Controlled Trials as Topic

Substances

  • Amino Acids
  • Intercellular Signaling Peptides and Proteins
  • Neuroprotective Agents
  • Oligopeptides
  • Peptide Fragments
  • Peptides
  • pinealon
  • cerebrolysin
  • ACTH (4-7), Pro-Gly-Pro-
  • cortexin
  • Adrenocorticotropic Hormone