Ductal hypoxia in acne: is it the missing link between comedogenesis and inflammation?

Frederick William Danby

doi:10.1016/j.jaad.2013.11.029

Ductal hypoxia in acne: is it the missing link between comedogenesis and inflammation?

J Am Acad Dermatol. 2014 May;70(5):948-9. doi: 10.1016/j.jaad.2013.11.029.

Author

Frederick William Danby¹

Affiliation

¹ Geisel School of Medicine at Dartmouth, Hanover, New Hampshire. Electronic address: billd860@gmail.com.

PMID: 24742839
DOI: 10.1016/j.jaad.2013.11.029

No abstract available

Keywords: acne; acnegenesis; adhesion molecules; hyperkeratosis; hypoxia; hypoxia inducible factor-1; neutrophil recruitment; terminal differentiation.

MeSH terms

Hidradenitis Suppurativa / physiopathology*
Humans
Hypoxia / physiopathology*
Hypoxia-Inducible Factor 1 / physiology
Inflammation / physiopathology
Keratinocytes / pathology
Keratinocytes / physiology
Keratins / metabolism

Substances

Hypoxia-Inducible Factor 1
Keratins