Subfoveal choroidal thickness in patients with chronic heart failure analyzed by spectral-domain optical coherence tomography

Curr Eye Res. 2014 Nov;39(11):1123-8. doi: 10.3109/02713683.2014.898310. Epub 2014 Apr 21.

Abstract

Purpose: To evaluate the subfoveal choroidal thickness (SFCT) measured by enhanced depth imaging optical coherence tomography (EDI-OCT) in eyes of chronic heart failure (CHF) patients.

Methods: Fifty-six patients with CHF and 56 age- and gender-matched healthy individuals were enrolled. The SFCT was measured by EDI-OCT. The ejection fraction of left ventricle (EFLV), age, intraocular pressure (IOP), axial length (AL), systolic and diastolic blood pressure, and ocular perfusion pressure (OPP) were also measured.

Results: Mean SFCT was 181.2 ± 80.23 μm in the study group and 283.6 ± 52.4 μm in the control group (p = 0.000). There was a statistically significant correlation between the SFCT and each of EFLV and age. SFCT value was not statistically significantly associated with AL, IOP and OPP.

Conclusion: Our results suggest that SFCT is lower in eyes of CHF patients compared to age- and gender-matched healthy individuals.

Keywords: Chronic heart failure; ejection fraction of left ventricle; enhanced depth imaging optical coherence tomography.

MeSH terms

  • Axial Length, Eye
  • Blood Pressure / physiology
  • Choroid / pathology*
  • Chronic Disease
  • Cross-Sectional Studies
  • Female
  • Fovea Centralis
  • Heart Failure / physiopathology*
  • Humans
  • Intraocular Pressure / physiology
  • Male
  • Middle Aged
  • Prospective Studies
  • Stroke Volume / physiology
  • Tomography, Optical Coherence*