Evaluation of retrobulbar blood flow with color doppler ultrasonography in patients with central serous chorioretinopathy

J Clin Ultrasound. 2014 Oct;42(8):481-5. doi: 10.1002/jcu.22156. Epub 2014 Apr 18.


Background: To compare retrobulbar blood flow in patients with central serous chorioretinopathy (CSC) and healthy subjects using color Doppler ultrasonography.

Methods: Thirty patients (age 23-54 years) with a first episode of acute CSC and 30 healthy controls (age 30-44 years) were evaluated. The peak systolic blood flow velocity, end-diastolic velocity (EDV), resistance index (RI), and pulsatility index (PI) were measured in the ophthalmic, posterior ciliary, and central retinal arteries.

Results: The posterior ciliary and central retinal artery EDV were lower in the patient group than in the control group, whereas RI and PI values were significantly higher (p < .05). The ophthalmic artery peak systolic blood flow velocity and EDV were lower in the CSC than in the control group (p < .05) without significant difference in RI and PI.

Conclusions: Color Doppler ultrasonography provides additional insights into the pathophysiology of CSC and may support the vasospasm hypothesis.

Keywords: central retinal artery; central serous chorioretinopathy; color Doppler ultrasonography; pulsatility index; resistance index.

MeSH terms

  • Adult
  • Central Serous Chorioretinopathy / diagnostic imaging
  • Central Serous Chorioretinopathy / physiopathology*
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Ophthalmic Artery / diagnostic imaging*
  • Ophthalmic Artery / physiopathology
  • Orbit / blood supply*
  • Regional Blood Flow / physiology*
  • Reproducibility of Results
  • Retrospective Studies
  • Ultrasonography, Doppler, Color / methods*
  • Young Adult