Combination of mechanical atherectomy and drug-eluting balloons for femoropopliteal in-stent restenosis

J Cardiovasc Surg (Torino). 2014 Jun;55(3):347-9.


Mechanical atherectomy for instent restenosis (ISR) seems to be limited by a low patency rate. This might be due to the mechanical trauma that induces an inflammatory response leading to recurrent ISR. Addition of drug eluting balloon angioplasty could overcome these challenges while preserving the advantages of a better acute result. Due to lack of clinical data combination of atherectomy and DEB remains an experimental procedure for ISR treatment.

Publication types

  • Review

MeSH terms

  • Angioplasty, Balloon / adverse effects
  • Angioplasty, Balloon / instrumentation*
  • Animals
  • Atherectomy / methods*
  • Constriction, Pathologic
  • Equipment Design
  • Femoral Artery* / physiopathology
  • Humans
  • Peripheral Arterial Disease / diagnosis
  • Peripheral Arterial Disease / physiopathology
  • Peripheral Arterial Disease / therapy*
  • Popliteal Artery* / physiopathology
  • Recurrence
  • Retreatment
  • Stents*
  • Treatment Outcome
  • Vascular Access Devices*
  • Vascular Patency