Confocal laser tomographic analysis of the retina in eyes with macular hole formation and other focal macular diseases

Am J Ophthalmol. 1989 Sep 15;108(3):277-87. doi: 10.1016/0002-9394(89)90118-9.


To study the retinal surface in the human eye in normal and diseased states we used laser scanning tomography. The confocal arrangement of the laser tomographic scanner permits examination of retinal topography in the axis perpendicular to the retinal surface. The eyes examined with the laser tomographic scanner included normal eyes, eyes with macular holes, impending macular holes, radiation retinopathy, macular edema, photocoagulation scars, subfoveal scars, and serous detachment of the fovea associated with subretinal neovascularization. The laser tomographic scanner is a new method that allows measurements of the topography of the internal limiting membrane in the macular area and may improve our understanding of the pathophysiologic characteristics and treatment of a variety of disorders of the macula.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Aged
  • Female
  • Humans
  • Image Processing, Computer-Assisted
  • Lasers*
  • Macula Lutea / pathology*
  • Male
  • Middle Aged
  • Neovascularization, Pathologic
  • Retina / pathology*
  • Retinal Diseases / diagnosis*
  • Retinal Perforations / diagnosis*
  • Retinal Vessels
  • Tomography / methods*