Background: Primary ciliary dyskinesia (PCD) and humoral mmunodeficiency (HID) are both rare disorders which cause recurrent upper and lower respiratory tract infections.
Objective: To examine the concurrence of PCD and HID in a patient cohort with known PCD.
Methods: Retrospective review of the patient files.
Results: We describe 11 patients of a cohort of 168 patients with PCD (6.5%) with a combination of PCD and some form of HID. The patients all presented with typical clinical symptoms for PCD, however the role of the concomitant immunological abnormalities is not clear.
Conclusion: PCD and HID coincided in 6.5% of the patients. We suggest that a common pathophysiological pathway results in both disorders.
Keywords: Antibody; Cilia; Humoral immunodeficiency; Primary ciliary dyskinesia.
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