Assessment of improved motion-sensitized driven equilibrium (iMSDE) for multi-contrast vessel wall screening

Magn Reson Med Sci. 2014;13(2):139-44. doi: 10.2463/mrms.2013-0036. Epub 2014 Apr 28.

Abstract

Purpose: We assessed the improved motion-sensitized driven equilibrium (iMSDE) technique for multiple contrast 3-dimensional vessel wall imaging at 3T.

Methods: Carotid images were obtained using iMSDE combined with turbo field echo (iMSDE-TFE) and conventional double inversion-recovery turbo spin-echo (DIR-TSE) in 5 healthy adult subjects. The tissue signal-to-noise efficiency (SNReff), SNR divided by the square root of scan time, lumen-tissue contrast-to-noise efficiency (CNReff), CNR divided by the square root of scan time, and tissue signal intensity ratio (SIR) were measured in both techniques and compared.

Results: The iMSDE-TFE had higher SNReff and CNReff (P < 0.01) and strong correlation in SIR (R = 0.92) compared to DIR-TSE.

Conclusion: The iMSDE-TFE sequence is an efficient technique for vessel wall screening.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Carotid Arteries / anatomy & histology*
  • Healthy Volunteers
  • Humans
  • Image Enhancement / methods
  • Image Interpretation, Computer-Assisted / methods
  • Imaging, Three-Dimensional
  • Magnetic Resonance Angiography / methods*
  • Motion
  • Signal-To-Noise Ratio