Extended-spectrum β-lactamase-producing Escherichia coli isolation among older adults: epidemiology and outcomes

Am J Infect Control. 2014 May;42(5):565-8. doi: 10.1016/j.ajic.2014.01.015.

Abstract

Clinical outcomes of older and younger adults with extended-spectrum β-lactamase-producing Escherichia coli isolation were compared. Two hundred thirty-two older adults (aged ≥65 years), and 145 younger adults with infection were identified between February 2010 and July 2011. After controlling for the propensity score and receipt of effective therapy, older adults were not at increased risk for adverse outcomes.

Keywords: Elderly adults; Gram-negative; Multidrug resistant.

Publication types

  • Comparative Study
  • Research Support, N.I.H., Extramural

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Anti-Bacterial Agents / therapeutic use*
  • Escherichia coli / enzymology*
  • Escherichia coli / isolation & purification*
  • Escherichia coli Infections / drug therapy*
  • Escherichia coli Infections / microbiology*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Risk Assessment
  • Treatment Failure
  • Young Adult
  • beta-Lactamases / metabolism*

Substances

  • Anti-Bacterial Agents
  • beta-Lactamases