Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
, 24 (11), 2412-4

Development of Bacterial Transglycosylase Inhibitors as New Antibiotics: Moenomycin A Treatment for Drug-Resistant Helicobacter Pylori

Affiliations

Development of Bacterial Transglycosylase Inhibitors as New Antibiotics: Moenomycin A Treatment for Drug-Resistant Helicobacter Pylori

Yen-Yu Tseng et al. Bioorg Med Chem Lett.

Abstract

The problem of multidrug-resistant Helicobacter pylori requires new antibiotics development. We have evaluated a potential antibiotics, moenomycin A, which is classified as a phosphoglycolipid antibiotics that targets transglycosylase and is previously thought to be limited in Gram-positive bacteria. Herein, we report the activity of moenomycin A against multidrug-resistant H. pylori and the isolates from patients with different gastrointestinal diseases.

Keywords: Antibiotics; Helicobacter pylori; Moenomycin; Transglycosylases.

Similar articles

See all similar articles

Cited by 4 articles

Publication types

MeSH terms

LinkOut - more resources

Feedback