Guidelines for pancreaticobiliary cytology from the Papanicolaou Society of Cytopathology: A review

Cancer Cytopathol. 2014 Jun;122(6):399-411. doi: 10.1002/cncy.21427. Epub 2014 Apr 28.


The newest installment on state-of-the-art standards of practice in cytopathology from the Papanicolaou Society of Cytopathology (PSC) focuses on the pancreaticobiliary system. Similar to the National Cancer Institute recommendations for aspiration cytology of the thyroid, the PSC guidelines for pancreaticobiliary cytology addresses indications, techniques, terminology and nomenclature, ancillary studies, and postprocedure management. Each committee was composed of a multidisciplinary group of experts in diagnosing, managing, and treating patients with pancreaticobiliary disease. Draft documents were posted on an interactive Web-based forum hosted by the PSC Web site ( and the topics of terminology, ancillary testing, and management were presented at national and international meetings over an 18-month period for discussion and feedback from practicing pathologists around the world. This review provides a synopsis of these guidelines.

Keywords: Papanicolaou Society of Cytopathology; guidelines; pancreas; review.

Publication types

  • Review

MeSH terms

  • Biliary Tract Neoplasms / pathology*
  • Cytodiagnosis / standards*
  • Humans
  • Pancreatic Neoplasms / pathology*
  • Papanicolaou Test*
  • Pathology, Clinical / standards*
  • Practice Guidelines as Topic*
  • Societies, Medical