Paroxysmal dysarthria-ataxia is a rare neurological condition due to ephaptic transmission, generally appearing in multiple sclerosis patients characterized by stereotyped attacks of slurred speech usually accompanied by ataxia, appearing many times a day. Here we describe a patient with an unusual remitting-relapsing form of Bickerstaff's-like brainstem encephalitis who manifested PDA after a relapse with the involvement of a peculiar region below the red nuclei and benefited from lamotrigine.
Keywords: Autoimmune diseases of the nervous system; Bickerstaff's brainstem encephalitis; Brainstem MRI abnormalities; Brainstem dysfunction; Ephaptic axonal activation; Paroxysmal dysarthria-ataxia syndrome.
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