Embryo culture and selection: morphological criteria

Methods Mol Biol. 2014;1154:501-32. doi: 10.1007/978-1-4939-0659-8_23.


In this chapter, we have outlined the various morphological criteria for selection of the best embryo at each important milestone encountered in the progress from the oocyte to the blastocyst. As Gerris et al. stated, a combination of one, two, or even three selection points should lead to a more accurate selection of the best embryo, as no one criterion is better than the other. An embryo that fails to meet the entire set of selection criteria must be avoided as culture cannot correct an impaired embryo.

MeSH terms

  • Blastocyst*
  • Embryo Culture Techniques / methods*
  • Embryo Implantation / physiology
  • Embryo Transfer / methods
  • Embryo, Mammalian / metabolism
  • Fertilization in Vitro / methods
  • Humans
  • Molecular Biology / methods