Diabetic kidney disease: a clinical update from Kidney Disease: Improving Global Outcomes

Kidney Int. 2015 Jan;87(1):20-30. doi: 10.1038/ki.2014.128. Epub 2014 Apr 30.


The incidence and prevalence of diabetes mellitus (DM) continue to grow markedly throughout the world, due primarily to the increase in type 2 DM (T2DM). Although improvements in DM and hypertension management have reduced the proportion of diabetic individuals who develop chronic kidney disease (CKD) and progress to end-stage renal disease (ESRD), the sheer increase in people developing DM will have a major impact on dialysis and transplant needs. This KDIGO conference addressed a number of controversial areas in the management of DM patients with CKD, including aspects of screening for CKD with measurements of albuminuria and estimated glomerular filtration rate (eGFR); defining treatment outcomes; glycemic management in both those developing CKD and those with ESRD; hypertension goals and management, including blockers of the renin-angiotensin-aldosterone system; and lipid management.

Publication types

  • Congress
  • Research Support, N.I.H., Intramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Albuminuria / etiology
  • Diabetic Nephropathies / complications
  • Diabetic Nephropathies / diagnosis*
  • Diabetic Nephropathies / therapy*
  • Disease Progression
  • Humans
  • Hyperglycemia / etiology
  • Hypertension / etiology