His overdrive pacing during supraventricular tachycardia: a novel maneuver for distinguishing atrioventricular nodal reentrant tachycardia from atrioventricular reciprocating tachycardia

Heart Rhythm. 2014 Aug;11(8):1327-35. doi: 10.1016/j.hrthm.2014.04.038. Epub 2014 May 2.


Background: Because the His bundle is intrinsic to the circuit in orthodromic reciprocating tachycardia and remote from that of atrioventricular nodal reentrant tachycardia (AVNRT), pacing the His bundle during supraventricular tachycardia (SVT) may be useful to distinguish these arrhythmias.

Objective: The purpose of this study was to test the hypothesis that His overdrive pacing (HOP) would affect SVT immediately for orthodromic reciprocating tachycardia and in a delayed manner for AVNRT.

Methods: Once SVT was induced, HOP was performed by pacing the His bundle 10-30 ms faster than the SVT cycle length. The maneuver was determined to have entered the tachycardia circuit when a nonfused His-capture beat advanced or delayed the subsequent atrial electrogram by ≥10 ms or when the tachycardia was terminated. The number of beats required to enter each tachycardia with HOP was recorded.

Results: HOP was performed during 66 SVTs (26 atrioventricular reciprocating tachycardia [AVRT] and 40 AVNRT). Entry into the tachycardia within 1 beat had sensitivity of 92%, specificity of 92%, positive predictive value (PPV) of 89% and negative predictive value (NPV) of 95% to confirm the diagnosis of AVRT. A cutoff ≥3 beats to enter the circuit had sensitivity of 90%, specificity of 92%, PPV of 95% and NPV of 86% to confirm the diagnosis of AVNRT. HOP had sensitivity, specificity, PPV, and NPV of 100% for distinguishing septal AVRT from atypical AVNRT.

Conclusion: HOP during SVT is a novel technique for distinguishing orthodromic reciprocating tachycardia from AVNRT. It can reliably distinguish between these arrhythmias with high sensitivity and specificity.

Keywords: Ablation; Atrioventricular nodal reentrant tachycardia; Atrioventricular reciprocating tachycardia; Entrainment; Supraventricular tachycardia.

MeSH terms

  • Adolescent
  • Adult
  • Bundle of His / physiopathology*
  • Cardiac Pacing, Artificial / methods*
  • Diagnosis, Differential
  • Electrocardiography
  • Electrophysiologic Techniques, Cardiac
  • Female
  • Follow-Up Studies
  • Heart Conduction System / physiopathology*
  • Humans
  • Male
  • Retrospective Studies
  • Tachycardia, Atrioventricular Nodal Reentry / diagnosis*
  • Tachycardia, Atrioventricular Nodal Reentry / physiopathology
  • Tachycardia, Atrioventricular Nodal Reentry / therapy
  • Tachycardia, Reciprocating / diagnosis*
  • Tachycardia, Reciprocating / physiopathology
  • Tachycardia, Reciprocating / therapy
  • Young Adult