Selective oxidative homo- and cross-coupling of phenols with aerobic catalysts

J Am Chem Soc. 2014 May 14;136(19):6782-5. doi: 10.1021/ja500183z. Epub 2014 May 5.

Abstract

Simple catalysts that use atom-economical oxygen as the terminal oxidant to accomplish selective ortho-ortho, ortho-para, or para-para homo-couplings of phenols are described. In addition, chromium salen catalysts have been discovered as uniquely effective in the cross-coupling of different phenols with high chemo- and regioselectivity.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Catalysis
  • Chromium / chemistry
  • Ethylenediamines / chemistry
  • Oxidants / chemistry*
  • Oxidation-Reduction
  • Oxygen / chemistry*
  • Phenols / chemistry*
  • Stereoisomerism

Substances

  • Ethylenediamines
  • Oxidants
  • Phenols
  • Chromium
  • disalicylaldehyde ethylenediamine
  • Oxygen