Radiation-induced osteosarcoma of the hand: case report

J Hand Surg Am. 2014 Jun;39(6):1151-4. doi: 10.1016/j.jhsa.2014.03.010. Epub 2014 May 3.

Abstract

Radiation-associated sarcomas represent less than 5% of all sarcomas and can arise from previously irradiated bone or soft tissue. We report a case of radiation-associated osteosarcoma that developed in the hand of a patient who had previously been treated for synovial sarcoma. Despite aggressive, multimodality treatment, the disease progressed rapidly. This case highlights the need for patients and treating physicians to be aware of this potential complication of radiotherapy to the hand.

Keywords: Radiation; hand; osteosarcoma; sarcoma.

Publication types

  • Case Reports

MeSH terms

  • Diagnosis, Differential
  • Fatal Outcome
  • Female
  • Hand*
  • Humans
  • Magnetic Resonance Imaging
  • Neoplasms, Radiation-Induced / diagnosis*
  • Neoplasms, Radiation-Induced / therapy
  • Osteosarcoma / etiology*
  • Salvage Therapy
  • Sarcoma, Synovial / radiotherapy
  • Young Adult