The tobacco genome sequence and its comparison with those of tomato and potato

Nat Commun. 2014 May 8;5:3833. doi: 10.1038/ncomms4833.

Abstract

The allotetraploid plant Nicotiana tabacum (common tobacco) is a major crop species and a model organism, for which only very fragmented genomic sequences are currently available. Here we report high-quality draft genomes for three main tobacco varieties. These genomes show both the low divergence of tobacco from its ancestors and microsynteny with other Solanaceae species. We identify over 90,000 gene models and determine the ancestral origin of tobacco mosaic virus and potyvirus disease resistance in tobacco. We anticipate that the draft genomes will strengthen the use of N. tabacum as a versatile model organism for functional genomics and biotechnology applications.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Base Sequence
  • DNA, Plant / genetics
  • Disease Resistance / genetics*
  • Disease Resistance / immunology
  • Gene Expression Profiling
  • Genetic Linkage
  • Genome, Plant
  • Lycopersicon esculentum / genetics*
  • Plant Diseases / immunology*
  • Plant Diseases / virology
  • Plant Leaves / genetics
  • Plant Roots / genetics
  • Potyvirus / pathogenicity
  • Sequence Alignment
  • Sequence Analysis, DNA
  • Solanum tuberosum / genetics*
  • Tobacco / classification
  • Tobacco / genetics*
  • Tobacco Mosaic Virus / pathogenicity

Substances

  • DNA, Plant