The effectiveness of nasal saline irrigation (seawater) in treatment of allergic rhinitis in children

Int J Pediatr Otorhinolaryngol. 2014 Jul;78(7):1115-8. doi: 10.1016/j.ijporl.2014.04.026. Epub 2014 May 5.

Abstract

Objective: To evaluate the effect of nasal saline irrigation in the treatment of allergic rhinitis (AR) in children and to assess whether nasal saline irrigation could be used as a complementary therapy for AR in children in combination with the intranasal corticosteroids (INS).

Method: In total, 61 children with AR were divided into three groups: the nasal irrigation, intranasal corticosteroid, and combined treatment groups. Symptoms and signs of AR and eosinophils (EOS) in the nasal secretions were evaluated after 4 weeks, 8 weeks, and 12 weeks of treatment.

Results: In AR children treated with nasal irrigation and a decreased the INS dose, a significant improvement in symptoms and signs and a significant decrease in the mean EOS count in nasal secretions were observed at week 12.

Conclusion: Nasal saline irrigation with physiological seawater is well tolerated and benefits the patients with AR, and can thus be considered a good adjunctive treatment option to maintain the effectiveness of the INS at a lower dose, thus resulting in reduced side effects and a decreased economic burden.

Keywords: Allergic rhinitis; Intranasal corticosteroids; Nasal saline irrigation; Seawater.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Administration, Intranasal
  • Adolescent
  • Child
  • Child, Preschool
  • Eosinophils / metabolism
  • Female
  • Glucocorticoids / administration & dosage
  • Humans
  • Male
  • Nasal Lavage*
  • Nasal Mucosa / metabolism
  • Rhinitis, Allergic / therapy*
  • Sodium Chloride / administration & dosage*

Substances

  • Glucocorticoids
  • Sodium Chloride