Hodgkin's disease: the Milan Cancer Institute experience with MOPP and ABVD

Recent Results Cancer Res. 1989:117:169-74. doi: 10.1007/978-3-642-83781-4_17.

Abstract

The report includes the essential therapeutic and toxic results following MOPP vs. MOPP/ABVD and MOPP vs. ABVD within a combined modality setting. The findings indicate that in stage IV the alternating regimen is superior to MOPP while in stage IIB-III ABVD plus radiotherapy yielded superior results associated with no treatment-induced sterility and leukemia compared with MOPP plus radiotherapy.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Bleomycin / administration & dosage
  • Combined Modality Therapy
  • Dacarbazine / administration & dosage
  • Doxorubicin / administration & dosage
  • Hodgkin Disease / drug therapy*
  • Humans
  • Mechlorethamine / administration & dosage
  • Prednisone / administration & dosage
  • Procarbazine / administration & dosage
  • Randomized Controlled Trials as Topic
  • Vinblastine
  • Vincristine / administration & dosage

Substances

  • Bleomycin
  • Procarbazine
  • Mechlorethamine
  • Vincristine
  • Vinblastine
  • Dacarbazine
  • Doxorubicin
  • Prednisone

Supplementary concepts

  • ABVD protocol
  • MOPP protocol