Healing of grafted adipose tissue: current clinical applications of adipose-derived stem cells for breast and face reconstruction

Wound Repair Regen. 2014 May;22 Suppl 1(0 1):11-3. doi: 10.1111/wrr.12164.


Since their isolation and characterization nearly a decade ago, adipose-derived stem cells (ASCs) have become one of the most popular adult stem cell populations for soft tissue engineering and regenerative medicine applications. Compared with other stem cell sources, ASCs offer several advantages including abundant autologous source, minor invasive harvesting (liposuction), significant proliferative capacity in culture, and multilineage potential. In this mini review, we focus on some of the more salient published clinical and preclinical data to date regarding ASC treatment for breast and facial soft tissue reconstruction.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Adipocytes / transplantation*
  • Adipose Tissue / cytology
  • Breast* / pathology
  • Face* / pathology
  • Female
  • Graft Survival
  • Humans
  • Lipectomy
  • Reconstructive Surgical Procedures* / methods
  • Regenerative Medicine
  • Stem Cell Transplantation* / methods
  • Tissue Engineering / methods
  • Transplantation, Autologous / methods*
  • Wound Healing*