Steroids in pediatric eosinophilic esophagitis

Gastroenterol Clin North Am. 2014 Jun;43(2):345-56. doi: 10.1016/j.gtc.2014.02.008. Epub 2014 Mar 29.


Swallowed fluticasone and oral viscous budesonide are effective first-line therapies for eosinophilic esophagitis in children. Side effects are minimal without evidence of Cushing syndrome, as seen in treatment with systemic corticosteroids. New studies on alternative delivery systems and different corticosteroids (eg, ciclesonide) are encouraging. As knowledge of corticosteroids in eosinophilic esophagitis expands, newer questions continue to arise concerning dose, delivery, and choice of corticosteroids; long-term adverse effects; and maintenance therapies.

Keywords: Budesonide; Children; Ciclesonide; Eosinophilic esophagitis; Fluticasone; Steroids; Topical steroids.

MeSH terms

  • Adrenal Cortex Hormones / therapeutic use*
  • Algorithms
  • Child
  • Eosinophilic Esophagitis / drug therapy*
  • Humans
  • Maintenance Chemotherapy


  • Adrenal Cortex Hormones