Angiopoietin-like 4, a protein strongly induced during sebocyte differentiation, regulates sebaceous lipogenesis but is dispensable for sebaceous gland function in vivo

J Dermatol Sci. 2014 Aug;75(2):148-50. doi: 10.1016/j.jdermsci.2014.04.008. Epub 2014 May 9.

Authors

Maik Dahlhoff¹, Emanuela Camera², Mauro Picardo², Christos C Zouboulis³, Marlon R Schneider⁴

Affiliations

¹ Institute of Molecular Animal Breeding and Biotechnology Gene Center, LMU Munich, Munich, Germany.
² Laboratory of Cutaneous Physiopathology and Integrated Center of Metabolomics Research, San Gallicano Dermatologic Institute, IRCCS, Rome, Italy.
³ Departments of Dermatology, Venereology, Allergology and Immunology, Dessau Medical Center, Dessau, Germany.
⁴ Institute of Molecular Animal Breeding and Biotechnology Gene Center, LMU Munich, Munich, Germany. Electronic address: schnder@lmb.uni-muenchen.de.

PMID: 24815769
DOI: 10.1016/j.jdermsci.2014.04.008

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Angiopoietin-Like Protein 4
Angiopoietins / deficiency
Angiopoietins / genetics
Angiopoietins / metabolism*
Animals
Cell Differentiation* / drug effects
Cell Line
Epithelial Cells / drug effects
Epithelial Cells / metabolism*
Humans
Linoleic Acid / pharmacology
Lipogenesis* / drug effects
Mice, Knockout
RNA Interference
RNA, Messenger / metabolism
Sebaceous Glands / cytology
Sebaceous Glands / drug effects
Sebaceous Glands / metabolism*
Thiazolidinediones / pharmacology
Time Factors
Transfection
Up-Regulation

Substances

ANGPTL4 protein, human
Angiopoietin-Like Protein 4
Angiopoietins
Angptl4 protein, mouse
RNA, Messenger
Thiazolidinediones
Linoleic Acid
ciglitazone