Chromatin dynamics from S-phase to mitosis: contributions of histone modifications

Cell Tissue Res. 2014 Jun;356(3):467-75. doi: 10.1007/s00441-014-1873-1. Epub 2014 May 10.

Abstract

This review focuses on the major protein moiety of chromosomes, i.e., the histone proteins, on the contribution of their posttranslational modification to structural and functional chromatin dynamics, on the acetylation and methylation of lysine residues, and on the phosphorylation of serine or threonine with respect to various steps during the cell cycle.

Publication types

  • Review

MeSH terms

  • Animals
  • Chromatin / genetics
  • Chromatin / metabolism*
  • Chromatin Assembly and Disassembly / physiology*
  • Humans
  • Mitosis / physiology*
  • S Phase / physiology*

Substances

  • Chromatin