Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2014;63(6):593-7.
doi: 10.5650/jos.ess14009. Epub 2014 May 15.

Effects of Xanthohumol-Rich Hop Extract on the Differentiation of Preadipocytes

Affiliations
Free article

Effects of Xanthohumol-Rich Hop Extract on the Differentiation of Preadipocytes

Ayane Kiyofuji et al. J Oleo Sci. .
Free article

Abstract

Xanthohumol is a major prenylated, hydrophobic flavonoid found in the female inflorescences of the hop plant (Humulus lupulus L.). In this study, we examined the effects of xanthohumol-rich hop extract containing 17.8% xanthohumol and 12.4% isoxanthohumol on the differentiation and adipogenesis of 3T3L1 cells. We observed that the extract inhibited the differentiation of 3T3L1 cells and intracellular fat droplets via the regulation of adipogenic factors such as the peroxisome proliferator-activated receptor gamma, CCAAT/enhancer binding protein alpha, and adipocyte fatty acid-binding protein.

Similar articles

See all similar articles

Cited by 5 articles

MeSH terms

Feedback