Catching bubbles: targeting ultrasound microbubbles using bioorthogonal inverse-electron-demand Diels-Alder reactions

Angew Chem Int Ed Engl. 2014 Jun 16;53(25):6459-63. doi: 10.1002/anie.201402473. Epub 2014 May 14.

Authors

Aimen Zlitni¹, Nancy Janzen, F Stuart Foster, John F Valliant

Affiliation

¹ Department of Chemistry and Chemical Biology, McMaster University, 1280 Main St W., Hamilton, Ont., L8S 4M1 (Canada).

PMID: 24829138
DOI: 10.1002/anie.201402473

No abstract available

Keywords: Diels-Alder reaction; antibodies; imaging agents; tetrazines; ultrasound.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Cell Line, Tumor
Contrast Media / chemistry*
Drug Delivery Systems
Humans
Microbubbles*
Molecular Structure
Tetrazoles / chemistry
Ultrasonics*

Substances

Contrast Media
Tetrazoles