[An analysis of the DNA synthesized in adenovirus-infected cells under exposure to nucleoside analogs]

Mikrobiol Zh (1978). 1989 Nov-Dec;51(6):73-5.
[Article in Russian]

Abstract

The method of dot DNA-DNA hybridization was used to reveal the inhibition of the synthesis of the adenoviral DNA by 6-azacytidine, cyclocytidine and ribamidyl in the adenovirus-infected cells Hep-2, a degree of which depended on the preparation concentration.

MeSH terms

  • Adenoviridae Infections / metabolism*
  • Adenovirus Infections, Human / metabolism*
  • Ancitabine / pharmacology
  • Azacitidine / analogs & derivatives
  • Azacitidine / pharmacology
  • Cells, Cultured / drug effects
  • Cells, Cultured / metabolism
  • DNA, Viral / analysis*
  • DNA, Viral / biosynthesis
  • Humans
  • Isomerism
  • Nucleic Acid Hybridization
  • Nucleosides / pharmacology*
  • Ribavirin / pharmacology

Substances

  • DNA, Viral
  • Nucleosides
  • Ribavirin
  • Ancitabine
  • Azacitidine
  • 6-azacytidine