Genomics in primary care practice

Prim Care. 2014 Jun;41(2):421-35. doi: 10.1016/j.pop.2014.02.012. Epub 2014 Mar 26.


This article discusses the clinical utility of genomic information for personalized preventive care of a healthy adult. Family health history is currently the most applicable genomic predictor for common, multifactorial diseases, and can also show patterns that suggest an inherited high susceptibility to a particular form of cancer or other disease. Both bloodline ancestry and shared environmental factors are important predictors for many disease states. DNA and family history analyses give information that is probabilistic, not deterministic. Therefore, family history can highlight behavioral, social, or cultural risk factors that can be modified to prevent diseases.

Keywords: Ancestry; Family health history; Genomic; Preventive care; Primary care; Value.

Publication types

  • Review

MeSH terms

  • Ethnicity / genetics
  • Family Health
  • Genetic Counseling
  • Genetic Predisposition to Disease / genetics*
  • Genetic Testing / methods*
  • Humans
  • Primary Health Care / organization & administration*
  • Racial Groups / genetics
  • Risk Assessment
  • Risk Factors