Squamous-lined cyst of the pancreas: Radiological-pathological correlation

Clin Radiol. 2014 Aug;69(8):880-6. doi: 10.1016/j.crad.2014.03.014. Epub 2014 May 16.


Pancreatic cystic lesions are increasingly being detected incidentally because of the increased use of cross-sectional imaging. Squamous-lined cysts of the pancreas (lymphoepithelial cyst, epidermoid cyst, and dermoid cyst) are rare cystic lesions lined with squamous epithelium. Distinguishing squamous-lined cysts from other cystic lesions of the pancreas is important to avoid unnecessary surgery, because squamous-lined cysts of the pancreas have no malignant potential. The purpose of this review is to describe findings on computed tomography and magnetic resonance imaging and the histopathological characteristics of squamous-lined cysts, and to summarize the key points of differential diagnosis for pancreatic cystic lesions.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Child
  • Dermoid Cyst / diagnosis
  • Diagnosis, Differential
  • Epidermal Cyst / diagnosis
  • Epithelium / diagnostic imaging
  • Epithelium / pathology
  • Female
  • Humans
  • Magnetic Resonance Imaging / methods*
  • Male
  • Middle Aged
  • Neoplasms, Squamous Cell / diagnostic imaging
  • Neoplasms, Squamous Cell / pathology
  • Pancreas / diagnostic imaging*
  • Pancreas / pathology*
  • Pancreatic Cyst / diagnosis*
  • Pancreatic Neoplasms / diagnostic imaging
  • Pancreatic Neoplasms / pathology
  • Tomography, X-Ray Computed / methods*
  • Young Adult