Remarkable regression of malignant paraganglioma in the retroperitoneum and neck after chemotherapy: report of a case and a review of the literature

Jpn J Med. 1989 Nov-Dec;28(6):772-6. doi: 10.2169/internalmedicine1962.28.772.

Abstract

The present communication describes a patient with paraganglioma found in the retroperitoneum and neck. She was treated with the combination chemotherapy employing cyclophosphamide, doxorubicin, and cisplatin (CAP therapy), and resulted in remarkable regression of the tumor in size. We reviewed the literature about the therapy of paraganglioma and the nature of retroperitoneal paraganglioma in relation with this case.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aclarubicin / administration & dosage
  • Adult
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Bleomycin / administration & dosage
  • Cisplatin / administration & dosage
  • Female
  • Head and Neck Neoplasms / diagnosis
  • Head and Neck Neoplasms / drug therapy*
  • Humans
  • Paraganglioma / diagnosis
  • Paraganglioma / drug therapy*
  • Peplomycin
  • Retroperitoneal Neoplasms / diagnosis
  • Retroperitoneal Neoplasms / drug therapy*
  • Tomography, X-Ray Computed
  • Ultrasonography

Substances

  • Bleomycin
  • Peplomycin
  • Aclarubicin
  • Cisplatin

Supplementary concepts

  • CAP therapy protocol