Antibiotics from myxobacteria

Nat Prod Rep. 2014 Jul;31(7):953-72. doi: 10.1039/c4np00011k. Epub 2014 May 19.

Abstract

Covering: up to the end of 2013. Myxobacteria produce a vast range of structurally diverse natural products with prominent biological activities. Here, we provide a detailed description and judge the potential of all antibiotically active myxobacterial compounds as lead structures, pointing out their particularities and, if known, their mode of action. Thus, the review provides an overview of the potential of specific compounds, suitable for future investigations and possible clinical applications.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Anti-Bacterial Agents* / chemistry
  • Anti-Bacterial Agents* / isolation & purification
  • Anti-Bacterial Agents* / pharmacology
  • Humans
  • Mice
  • Molecular Structure
  • Myxococcales* / chemistry
  • Myxococcales* / metabolism
  • Rats

Substances

  • Anti-Bacterial Agents