Finding a niche for cardiac precursors

Benoit G Bruneau

doi:10.7554/eLife.02993

Finding a niche for cardiac precursors

Elife. 2014 May 6:3:e02993. doi: 10.7554/eLife.02993.

Author

Benoit G Bruneau¹

Affiliation

¹ Benoit G Bruneau is in the Gladstone Institute of Cardiovascular Disease, and Roddenberry Center for Stem Cell Biology and Medicine at Gladstone, San Francisco, United States, and the Department of Pediatrics and Cardiovascular Research Institute, University of California, San Francisco, United States bbruneau@gladstone.ucsf.edu.

Abstract

Within an embryo, a region next to the developing heart provides a niche where cardiac precursor cells can increase in number before they contribute to the development of this organ.

Keywords: cardiac progenitor; heart; microenvironment; niche; numb; self-renewal.

Publication types

Comment

MeSH terms

Animals
Gene Deletion*
Membrane Proteins / physiology*
Myocytes, Cardiac / cytology*
Nerve Tissue Proteins / physiology*
Stem Cells / cytology*

Substances

Membrane Proteins
Nerve Tissue Proteins