Extramedullary pulmonary hematopoiesis causing pulmonary hypertension and severe tricuspid regurgitation detected by technetium-99m sulfur colloid bone marrow scan and single-photon emission computed tomography/CT

Korean J Radiol. 2014 May-Jun;15(3):376-80. doi: 10.3348/kjr.2014.15.3.376. Epub 2014 Apr 29.

Abstract

Extramedullary pulmonary hematopoiesis is a rare entity with a limited number of case reports in the available literature only. We report the case of a 66-year-old man with known primary myelofibrosis, in whom a Technetium-99m sulfur colloid bone marrow scan with single-photon emission computed tomography (SPECT)/CT revealed a pulmonary hematopoiesis as the cause of pulmonary hypertension and severe tricuspid regurgitation. To the best of our knowledge, this is the first description of Technetium-99m sulfur colloid SPECT/CT imaging in this rare condition.

Keywords: Extramedullary pulmonary hematopoiesis; Pulmonary hypertension; SPECT/CT; Technetium-99m sulfur colloid bone marrow scan; Tricuspid regurgitation.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Bone Marrow / diagnostic imaging*
  • Hematopoiesis, Extramedullary*
  • Humans
  • Hypertension, Pulmonary / diagnostic imaging
  • Hypertension, Pulmonary / etiology*
  • Lung / diagnostic imaging*
  • Male
  • Primary Myelofibrosis / complications
  • Technetium Tc 99m Sulfur Colloid
  • Tomography, Emission-Computed, Single-Photon / methods
  • Tomography, X-Ray Computed
  • Tricuspid Valve Insufficiency / diagnostic imaging
  • Tricuspid Valve Insufficiency / etiology*

Substances

  • Technetium Tc 99m Sulfur Colloid