Evolution: the advantage of 'maladaptive' pain plasticity

Curr Biol. 2014 May 19;24(10):R384-6. doi: 10.1016/j.cub.2014.04.011.


Following injury, nociceptive systems become sensitized, leading to heightened pain perception. The evolutionary reason for this phenomenon has been hard to pinpoint. A study in squid now suggests that nociceptive sensitization enhances survival from predators.

Publication types

  • Comment

MeSH terms

  • Animals
  • Decapodiformes / physiology*
  • Female
  • Food Chain*
  • Male
  • Nociception*