Comparative evaluation of two chromogenic tests for rapid detection of carbapenemase in Enterobacteriaceae and in Pseudomonas aeruginosa isolates

J Clin Microbiol. 2014 Aug;52(8):3060-3. doi: 10.1128/JCM.00643-14. Epub 2014 May 21.


We compared the performance of the Carba NP test and the Rosco Rapid CARB screen kit for detecting carbapenemase-producing Enterobacteriaceae and Pseudomonas aeruginosa. Both tests are rapid and highly sensitive; however, the Carba NP test showed superior specificity, and several uninterpretable results were observed with the Rapid CARB screen.

Publication types

  • Comparative Study
  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacterial Proteins / analysis*
  • Chromogenic Compounds / analysis*
  • Enterobacteriaceae / enzymology*
  • Humans
  • Microbial Sensitivity Tests / methods
  • Pseudomonas aeruginosa / enzymology*
  • Sensitivity and Specificity
  • Time Factors
  • beta-Lactamases / analysis*


  • Bacterial Proteins
  • Chromogenic Compounds
  • beta-Lactamases
  • carbapenemase