Gadolinium contrast agents for CNS imaging: current concepts and clinical evidence

E Kanal; K Maravilla; H A Rowley

doi:10.3174/ajnr.A3917

Gadolinium contrast agents for CNS imaging: current concepts and clinical evidence

AJNR Am J Neuroradiol. 2014 Dec;35(12):2215-26. doi: 10.3174/ajnr.A3917. Epub 2014 May 22.

Authors

E Kanal¹, K Maravilla², H A Rowley³

Affiliations

¹ From Magnetic Resonance Services (E.K.), Department of Radiology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
² Research Laboratory (K.M.), University of Washington, Seattle, Washington.
³ Departments of Radiology, Neurology, and Neurosurgery (H.A.R.), University of Wisconsin, Madison, Wisconsin. HRowley@UWHealth.org.

Abstract

The aim of this article was to review the properties of the various gadolinium-based contrast agents used for CNS imaging along with the clinical evidence and published data that highlight the impact these different properties can have on diagnostic performance. In addition, approaches to optimizing image acquisition that take into account the different properties of specific gadolinium-based contrast agents and an extensive review of the safety profiles of the various agents are presented.

Publication types

Review

MeSH terms

Contrast Media*
Gadolinium*
Humans
Image Interpretation, Computer-Assisted / methods*
Magnetic Resonance Imaging / methods*
Neuroimaging / methods*

Substances

Contrast Media
Gadolinium