The Brassica oleracea genome reveals the asymmetrical evolution of polyploid genomes

Nat Commun. 2014 May 23;5:3930. doi: 10.1038/ncomms4930.

Abstract

Polyploidization has provided much genetic variation for plant adaptive evolution, but the mechanisms by which the molecular evolution of polyploid genomes establishes genetic architecture underlying species differentiation are unclear. Brassica is an ideal model to increase knowledge of polyploid evolution. Here we describe a draft genome sequence of Brassica oleracea, comparing it with that of its sister species B. rapa to reveal numerous chromosome rearrangements and asymmetrical gene loss in duplicated genomic blocks, asymmetrical amplification of transposable elements, differential gene co-retention for specific pathways and variation in gene expression, including alternative splicing, among a large number of paralogous and orthologous genes. Genes related to the production of anticancer phytochemicals and morphological variations illustrate consequences of genome duplication and gene divergence, imparting biochemical and morphological variation to B. oleracea. This study provides insights into Brassica genome evolution and will underpin research into the many important crops in this genus.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Arabidopsis / genetics
  • Brassica / genetics*
  • Conserved Sequence
  • DNA Transposable Elements / genetics
  • Evolution, Molecular*
  • Gene Conversion
  • Gene Dosage
  • Gene Duplication
  • Gene Rearrangement / genetics
  • Genes, Duplicate
  • Genes, Plant
  • Genetic Variation
  • Genome, Plant*
  • Glucosinolates / metabolism
  • Molecular Sequence Annotation
  • Polyploidy*
  • Species Specificity
  • Synteny / genetics

Substances

  • DNA Transposable Elements
  • Glucosinolates

Associated data

  • GEO/GSE42891
  • GEO/GSE43245