Survey of intravitreal injection techniques and treatment protocols among retina specialists in Canada

Can J Ophthalmol. 2014 Jun;49(3):261-6. doi: 10.1016/j.jcjo.2014.03.009.

Abstract

Objective: To describe intravitreal injection (IVI) techniques and treatment protocols by retina specialists in Canada from August 1, 2012, to October 1, 2012.

Design: Cross-sectional survey.

Participants: All fellowship-trained retina specialists across Canada, as identified from the Canadian Ophthalmological Society directory and the Canadian Retina and Vitreous Society directory.

Methods: An anonymous 28-question survey was sent to 125 retina specialists across Canada by email. Reminder letters were sent by email, mail, and fax as necessary.

Results: A total of 75 (63%) retina specialists responded to the survey. Most IVIs were performed in the office. Most surgeons did not use gloves (61%), sterile draping (91%), or surgical mask (71%). Antisepsis was used on conjunctiva by 100% and on periocular skin by 48%. Nearly all specialists used a sterile lid speculum (91%). Common anaesthetics included topical proparacaine or lidocaine drops (90%), topical lidocaine gel (25%), topical pledget (23%), and subconjunctival lidocaine injections (23%). Most (83%) dilate the pupil before IVI. Prophylactic topical antibiotics were used by 43%; 50% of these were started immediately after IVI. Injection location was estimated by visualization by 45%. A majority (63%) inject inferotemporally. Anterior chamber paracentesis was performed routinely by 5%. Optic nerve perfusion was formally assessed by 48%. The most common treatment protocol for age-related macular degeneration was treat and extend. For both diabetic and retinal vein occlusion-related macular edema, the most common protocol was 3 initial monthly injections with PRN follow-up.

Conclusions: A wide variety of IVI practice patterns exist in terms of aseptic technique, anaesthetics, prophylactic antibiotics, postinjection monitoring, and treatment protocol.

MeSH terms

  • Administration, Topical
  • Anesthesia, Local / statistics & numerical data
  • Anti-Bacterial Agents / administration & dosage
  • Canada
  • Clinical Protocols
  • Cross-Sectional Studies
  • Female
  • Health Surveys
  • Humans
  • Intravitreal Injections / methods*
  • Intravitreal Injections / statistics & numerical data
  • Macular Degeneration / drug therapy
  • Macular Edema / drug therapy
  • Male
  • Middle Aged
  • Ophthalmic Solutions / administration & dosage*
  • Ophthalmology*
  • Practice Patterns, Physicians'*
  • Retina
  • Retinal Diseases / drug therapy*
  • Retinal Vein Occlusion / drug therapy
  • Specialization*
  • Surveys and Questionnaires

Substances

  • Anti-Bacterial Agents
  • Ophthalmic Solutions