Lifestyle Intervention Involving Calorie Restriction With or Without Aerobic Exercise Training Improves Liver Fat in Adults With Visceral Adiposity

J Obes. 2014;2014:197216. doi: 10.1155/2014/197216. Epub 2014 Apr 17.

Abstract

Objective: To evaluate the effect of calorie restriction-induced weight loss with or without aerobic exercise on liver fat.

Methods: Thirty-three adults with visceral adiposity were divided into calorie restriction (CR; n = 18) or CR and aerobic exercise (CR + Ex; n = 15) groups. Target energy intake was 25 kcal/kg of ideal body weight. The CR + Ex group had a targeted exercise time of 300 min/wk or more at lactate threshold intensity for 12 weeks.

Results: Reductions in body weight (CR, -5.3 ± 0.8 kg; CR + Ex, -5.1 ± 0.7 kg), fat mass (CR, -4.9 ± 0.9 kg; CR + Ex, -4.4 ± 0.6 kg), and visceral fat (CR, -24 ± 5 cm2; CR + Ex, -37 ± 5 cm2) were not statistically different between groups. Liver fat decreased significantly in both groups, with no difference between groups. Change in maximal oxygen uptake was significantly greater in the CR + Ex group than in the CR group (CR, -0.7 ± 0.7 mL/kg/min; CR + Ex, 2.9 ± 1.0 mL/kg/min).

Conclusion: Both CR and CR + Ex resulted in an improved reduction in liver fat; however, there was no additive effect of exercise training.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adiposity*
  • Adult
  • Caloric Restriction*
  • Exercise / physiology*
  • Female
  • Humans
  • Intra-Abdominal Fat / metabolism*
  • Life Style
  • Liver / metabolism*
  • Male
  • Middle Aged
  • Non-alcoholic Fatty Liver Disease* / metabolism
  • Non-alcoholic Fatty Liver Disease* / prevention & control
  • Obesity, Abdominal / metabolism
  • Overweight / metabolism
  • Overweight / therapy
  • Oxygen Consumption
  • Physical Exertion / physiology
  • Weight Loss*