Antimicrobial resistance and susceptibility testing of anaerobic bacteria

Clin Infect Dis. 2014 Sep 1;59(5):698-705. doi: 10.1093/cid/ciu395. Epub 2014 May 27.


Infections due to anaerobic bacteria can be severe and life-threatening. Susceptibility testing of anaerobes is not frequently performed in laboratories, but such testing is important to direct appropriate therapy. Anaerobic resistance is increasing globally, and resistance trends vary by geographic region. An overview of a variety of susceptibility testing methods for anaerobes is provided, and the advantages and disadvantages of each method are reviewed. Specific clinical situations warranting anaerobic susceptibility testing are discussed.

Keywords: anaerobe; anaerobic bacteria; resistance; susceptibility; susceptibility test methods.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents / pharmacology
  • Bacteria, Anaerobic / drug effects*
  • Drug Resistance, Microbial
  • Laboratories
  • Microbial Sensitivity Tests / methods*
  • Microbial Sensitivity Tests / standards*


  • Anti-Bacterial Agents