Recently achieved techniques in the field of stem cell research have permitted the development of human induced pluripotent stem cells (hiPSCs). The characteristics of these cells and their appearance after the passage of Order SCO/393/2006, of 8 February, on Functioning and Organization of a National Bank of Cell Lines and Act 14/2007, of 3 July, on Biomedical Research raise the questions of the legal regime of their deposition at the National Bank of Cell Lines and their control by the Commission of Guarantees for the Donation and Use of Human Cells and Tissues. Drawing on a wider legal frame, the author defends these requirements on the grounds that the legal classification comes from the origin and potentiality of the cells rather than from the techniques employed to obtain them.