When aryldiazonium salts meet vinyl diazoacetates: a cobalt-catalyzed regiospecific synthesis of N-arylpyrazoles

Org Lett. 2014 Jun 6;16(11):3110-3. doi: 10.1021/ol5012339. Epub 2014 May 29.

Abstract

A cobalt-catalyzed C-N bond formation between aryl diazonium salts and vinyl diazoacetates has been developed under relatively mild conditions. The N-arylpyrazoles have been prepared in moderate to high yields in a regiospecific way.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Azo Compounds / chemistry*
  • Catalysis
  • Cobalt / chemistry*
  • Diazonium Compounds / chemistry*
  • Molecular Structure
  • Pyrazoles / chemical synthesis*
  • Pyrazoles / chemistry*
  • Salts / chemistry*

Substances

  • Azo Compounds
  • Diazonium Compounds
  • Pyrazoles
  • Salts
  • Cobalt