Perioperative outcome of esophageal fundoplication for gastroesophageal reflux disease in obese and morbidly obese patients

Am J Surg. 2014 Aug;208(2):163-8. doi: 10.1016/j.amjsurg.2014.02.010. Epub 2014 Apr 24.


Background: To determine the perioperative safety of esophageal fundoplication for gastroesophageal reflux disease (GERD) in patients with body mass index (BMI) ≥ 35 kg/m(2).

Methods: A retrospective review of 4,231 patients who underwent fundoplication for GERD from 2005 to 2009 was performed. Patients were identified via National Surgical Quality Improvement Program and grouped by BMI < 35 versus BMI ≥ 35 kg/m(2). Univariate analysis compared 30-day outcomes.

Results: Of the 4,231 patients, 3,496 (83%) had BMI < 35 kg/m(2) and 735 (17%) had BMI ≥ 35 kg/m(2). Mean BMI for each cohort was 27.9 versus 39.1, respectively. Patients with BMI ≥ 35 kg/m(2) had significantly longer operative times (129.7 vs 118 minutes, P < .0001) and increased American Society of Anesthesiologists scores (2.43 vs 2.3, P = .001). The overall complication rate was 1.96%. No difference was demonstrated by BMI in complication rate or hospital length of stay. Increased American Society of Anesthesiologists score, diabetes, black race, longer operative time, and intraoperative transfusion significantly increased postoperative complication rates.

Conclusions: No increased risk is conferred to morbidly obese patients who undergo fundoplication for GERD management. This study identified independent patient risk factors for postoperative complication following esophageal fundoplication.

Keywords: Complications; Fundoplication; Gastroesophageal reflux; Morbid obesity; Outcomes.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Comorbidity
  • Female
  • Fundoplication*
  • Gastroesophageal Reflux / epidemiology
  • Gastroesophageal Reflux / surgery*
  • Humans
  • Male
  • Middle Aged
  • Obesity / epidemiology*
  • Obesity, Morbid / epidemiology
  • Postoperative Complications / epidemiology*
  • Risk Factors
  • Treatment Outcome