Caesarean scar choriocarcinoma: a case report and review of the literature

Eur J Med Res. 2014 May 14;19(1):25. doi: 10.1186/2047-783X-19-25.

Abstract

Objective: To report the clinical characteristics, pathologic findings and treatments of a patient with a Caesarean scar choriocarcinoma.

Patient history: A 22-year-old woman had a diagnosis of primary gestational choriocarcinoma in a uterine Caesarean scar misdiagnosed as a normal Caesarean scar pregnancy. The patient underwent selective uterine artery embolization coupled with methotrexate arterial injection, along with dilatation and curettage of the uterine Caesarean scar. Finally, she received eight courses of multiagent chemotherapy. The reproductive function of the patient was preserved.

Conclusions: Primary gestational choriocarcinoma out of the uterine corpus is a rare disease. A Caesarean scar choriocarcinoma is an extremely unusual example of this entity because of its unique position. To the best of our knowledge, this is the first report of this phenomenon. Our experience and a literature review suggest that a clinical diagnosis of a primary gestational choriocarcinoma of the uterine Caesarean scar is difficult to make, and uterine artery embolization is beneficial to prevent massive bleeding before curettage.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Antineoplastic Agents / administration & dosage
  • Cesarean Section*
  • Choriocarcinoma / pathology*
  • Choriocarcinoma / therapy
  • Cicatrix / pathology*
  • Female
  • Humans
  • Methotrexate / administration & dosage
  • Pregnancy
  • Uterine Artery Embolization
  • Uterine Neoplasms / pathology*
  • Uterine Neoplasms / therapy
  • Young Adult

Substances

  • Antineoplastic Agents
  • Methotrexate