Musculoskeletal deformities following repair of large congenital diaphragmatic hernias

J Pediatr Surg. 2014 Jun;49(6):886-9. doi: 10.1016/j.jpedsurg.2014.01.018. Epub 2014 Feb 5.

Abstract

Purpose: Large congenital diaphragmatic hernias (CDH) can be repaired with either a muscle flap or prosthetic patch. The purpose of this study was to assess the frequency and severity of scoliosis, chest wall, and abdominal wall deformities following these repairs.

Methods: Neonates who underwent CDH repair (1989-2012) were retrospectively reviewed. We then validated our retrospective review by comparing results of a focused radiologic evaluation and clinical examination of patients with large defects seen in prospective follow-up clinic. Tests for association were made using Fisher's exact test.

Results: 236 patients survived at least 1year. Of these patients, 30 had a muscle flap, and 13 had a patch repair. Retrospectively, we identified pectus in 9% of primary repairs, 47% of flap repairs, and 54% of patch repairs. We identified scoliosis in 7% of primary repairs, 13% of flap repairs, and 15% of patch repairs. Prospectively, 75% of flap patients and 67% of patch patients had pectus and 13% of flap patients and 33% of patch patients had scoliosis. There was no significant difference between flap and patch patients.

Conclusions: Scoliosis and pectus deformity were common in children with large CDH. The operative technique did not appear to affect the incidence of subsequent skeletal deformity.

Keywords: CDH; Pectus carinatum; Pectus excavatum; Scoliosis; Split-abdominal wall muscle flap.

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Female
  • Follow-Up Studies
  • Hernias, Diaphragmatic, Congenital / surgery*
  • Herniorrhaphy / adverse effects*
  • Humans
  • Incidence
  • Infant
  • Infant, Newborn
  • Male
  • Musculoskeletal Diseases / epidemiology
  • Musculoskeletal Diseases / etiology*
  • Postoperative Complications*
  • Retrospective Studies
  • Risk Factors
  • Surgical Flaps / adverse effects*
  • Surgical Mesh / adverse effects*
  • United States / epidemiology
  • Young Adult