Report of the joint ESOT and TTS basic science meeting 2013: current concepts and discoveries in translational transplantation

Transpl Int. 2014 Oct;27(10):987-93. doi: 10.1111/tri.12366. Epub 2014 Jun 30.

Abstract

A joint meeting organized by the European (ESOT) and The Transplantation (TTS) Societies for basic science research was organized in Paris, France, on November 7-9, 2013. Focused on new ideas and concepts in translational transplantation, the meeting served as a venue for state-of-the-art developments in basic transplantation immunology, such as the potential for tolerance induction through regulation of T-cell signaling. This meeting report summarizes important insights which were presented in Paris. It not only offers an overview of established aspects, such as the role of Tregs in transplantation, presented by Nobel laureate Rolf Zinkernagel, but also highlights novel facets in the field of transplantation, that is cell-therapy-based immunosuppression or composite tissue transplantation as presented by the emotional story given by Vasyly Rohovyy, who received two hand transplants. The ESOT/TTS joint meeting was an overall productive and enjoyable platform for basic science research in translational transplantation and fulfilled all expectations by giving a promising outlook for the future of research in the field of immunological transplantation research.

Keywords: bone marrow transplantation; cell and tissue transplantation; experimental transplantation; immunosuppression; tolerance strategies.

Publication types

  • Review

MeSH terms

  • Animals
  • Clinical Trials as Topic
  • Disease Models, Animal
  • France
  • Graft Rejection
  • Graft Survival
  • Humans
  • Immunity, Innate / immunology*
  • Immunity, Innate / physiology
  • Mice
  • Organ Transplantation / standards*
  • Organ Transplantation / trends
  • Societies, Medical
  • T-Lymphocytes / immunology
  • Translational Medical Research
  • Transplantation Immunology / physiology*
  • Transplantation Tolerance / immunology*