Cytoskeleton: cirque du septins

Curr Biol. 2014 Jun 2;24(11):R526-8. doi: 10.1016/j.cub.2014.04.030.

Abstract

Septins and F-actin are familiar cohabitants of the cleavage furrow yet how they might be functionally connected has been ambiguous. New work shows that septins can promote the assembly of curved bundles of F-actin, providing an unexpected molecular function for septins in cytokinesis.

Publication types

  • Comment

MeSH terms

  • Actin Cytoskeleton / metabolism*
  • Actins / metabolism*
  • Animals
  • Humans
  • Septins / metabolism*

Substances

  • Actins
  • Septins