Probiotic-associated aspiration pneumonia due to Lactobacillus rhamnosus

Christopher D Doern; Sean T Nguyen; Folashade Afolabi; Carey-Ann D Burnham

doi:10.1128/JCM.01065-14

Probiotic-associated aspiration pneumonia due to Lactobacillus rhamnosus

J Clin Microbiol. 2014 Aug;52(8):3124-6. doi: 10.1128/JCM.01065-14. Epub 2014 Jun 4.

Authors

Christopher D Doern¹, Sean T Nguyen², Folashade Afolabi³, Carey-Ann D Burnham⁴

Affiliations

¹ Virginia Commonwealth University Health System, Department of Pathology, Richmond, Virginia, USA cdoern@mcvh-vcu.edu.
² Children's Medical Center, Department of Pharmacy, Dallas, Texas, USA.
³ Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
⁴ Washington University School of Medicine, Department of Pathology and Immunology and Department of Pediatrics, St. Louis, Missouri, USA.

Abstract

Lactobacilli are low-virulence, commensal organisms of the gastrointestinal and genitourinary tracts and are commonly used as "probiotic supplements." Herein, we describe an episode of respiratory syncytial virus (RSV) bronchiolitis with bacterial superinfection secondary to administration of Lactobacillus rhamnosus in an 11-month-old female with trisomy 21.

Publication types

Case Reports

MeSH terms

Bacterial Infections / diagnosis*
Bacterial Infections / microbiology
Bacterial Infections / pathology
Down Syndrome / complications*
Female
Humans
Infant
Lacticaseibacillus rhamnosus / isolation & purification*
Pneumonia, Aspiration / diagnosis*
Pneumonia, Aspiration / microbiology*
Probiotics / administration & dosage*
Respiratory Syncytial Virus Infections / complications
Respiratory Syncytial Virus Infections / diagnosis*
Respiratory Syncytial Virus Infections / pathology