Overcoming Drug Development Bottlenecks With Repurposing: Repurposing biguanides to target energy metabolism for cancer treatment

Nat Med. 2014 Jun;20(6):591-3. doi: 10.1038/nm.3596.
No abstract available

MeSH terms

  • Clinical Trials as Topic / trends
  • Drug Repositioning / methods*
  • Drug Repositioning / trends*
  • Energy Metabolism / drug effects*
  • Guanidines / pharmacology*
  • Guanidines / therapeutic use
  • Humans
  • Metformin
  • Neoplasms / drug therapy*

Substances

  • Guanidines
  • Metformin