Feasible Method to enable clear visualization of suspected bladder cancer with 18F-FDG PET/CT

Clin Imaging. 2014 Sep-Oct;38(5):704-9. doi: 10.1016/j.clinimag.2014.04.018. Epub 2014 May 9.

Abstract

Purpose: To evaluate value of a new method in detecting bladder lesion with (18)F-FDG PET/CT.

Methods: Routine and delayed scans of 14 patients were retrospectively studied. All these bladder lesions were confirmed by pathology. By increasing display threshold of SUVmax, routine images were analyzed for the second time.

Results: Of 12 (18)F-FDG-avid cases, 10 cases were confirmed to be primary bladder carcinoma, 2 false-positive cases were inflammation. There were 25% positive cases on routine display and 50% on display with increased SUVmax threshold.

Conclusion: The method can effectively increase the sensitivity and accuracy in detecting bladder cancer with (18)F-FDG PET/CT.

Keywords: (18)F-FDG; Bladder cancer; Delayed imaging; PET/CT.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Cystoscopy
  • Diagnosis, Differential
  • Feasibility Studies
  • Female
  • Fluorodeoxyglucose F18*
  • Follow-Up Studies
  • Humans
  • Image Processing, Computer-Assisted / methods*
  • Male
  • Middle Aged
  • Neoplasm Staging
  • Positron-Emission Tomography / methods*
  • Radiopharmaceuticals
  • Reproducibility of Results
  • Retrospective Studies
  • Tomography, X-Ray Computed / methods*
  • Urinary Bladder Neoplasms / diagnosis*
  • Whole Body Imaging / methods*

Substances

  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18